Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.66 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9573567 | 0.98 | CA2 (0.64) | CA2HTR6CA1KDM1APOLB | |
| SCHEMBL17526253 | 0.82 | HTR6 (0.56) | CA2HTR6CA1POLBDDX3X | |
| SCHEMBL5250781 | 0.79 | CA2 (0.61) | CA2CA1KDM1APTPN1PTPN11 | |
| SCHEMBL6426214 | 0.79 | CA2 (0.61) | CA2CA1PTPN11MEN1GAA | |
| SCHEMBL9200704 | 0.79 | CA2 (0.61) | CA2CA1KDM1APTPN1PTPN11 | |
| SCHEMBL12153756 | 0.79 | CA2 (0.61) | CA2CA1KDM1APTPN1PTPN11 | |
| SCHEMBL30990110 | 0.79 | CA2 (0.61) | CA2CA1PTPN11MEN1GAA | |
| SCHEMBL7118308 | 0.79 | CA2 (0.61) | CA2CA1KDM1APTPN1PTPN11 | |
| SCHEMBL4049597 | 0.77 | CA2 (0.67) | CA2CA1PTPN1PTPN11MEN1 | |
| SCHEMBL8547020 | 0.77 | HTR6 (0.62) | CA2HTR6CA1POLBDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714667-B1 | AMINOOXAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | DESAI LAXMAN S (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-2714667-B1 | AMINOOXAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | DESAI LAXMAN S (US) | 2020-11-25 | — | — | EP | disclosed |
| US-8865709-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865709-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2014-10-21 | — | — | US | disclosed |
| US-8865709-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2014-10-21 | — | — | US | disclosed |
| US-20140051694-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2014-02-20 | — | — | US | disclosed |
| US-20140051694-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2014-02-20 | — | — | US | disclosed |
| US-8551992-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551992-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8551992-B2 | Aminooxazole inhibitors of cyclin dependent kinases | Neosome Life Sciences, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | Neosome Life Sciences, LLC (US) | 2012-11-29 | — | — | US | disclosed |
| US-20080261973-A1 | Sulphonamidoaniline Derivatives Being Janus Kinase Inhibitors | NOVARTIS AG (CH) | 2008-10-23 | — | — | US | disclosed |
| EP-1966210-A2 | SULPHONAMIDOANILINE DERIVATIVES BEING JANUS KINASES INHIBITORS | Novartis AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071393-A2 | SULPHONAMIDOANILINE DERIVATIVES BEING JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| CN-1074216-A | Urea derivative | GLAXO GROUP LTD (GB) | 1993-07-14 | — | — | CN | disclosed |
| WO-1993008175-A1 | BENZODIAZEPINE DERIVATIVES AS ANTAGONISTS OF GASTRIN AND/OR CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538945-A1 | Benzodiazepine derivatives, and their use as antagonists of gastrin and/or cholecystokinin | GLAXO GROUP LIMITED (GB) | 1993-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184288-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | CDK1, CCNK, CCNI | CA2 2537/4885HTR6 3264/4885CA1 1400/4885 |
| US-20120302578-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | CDK1, CCNK, CCNI | CA2 2537/4885HTR6 3264/4885CA1 1400/4885 |
| US-20140051694-A1 | Aminooxazole Inhibitors of Cyclin Dependent Kinases | CDK1, CCNK, CCNI | CA2 2537/4885HTR6 3264/4885CA1 1400/4885 |
| US-20080261973-A1 | Sulphonamidoaniline Derivatives Being Janus Kinase Inhibitors | GRK4, JAK2, ALK | CA2 2347/4885HTR6 3288/4885CA1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.