Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.78 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302608 | 0.88 | CCR2 (1.00) | CCR2 | |
| SCHEMBL4649521 | 0.85 | CCR2 (0.58) | CCR2RECQLMAPT | |
| SCHEMBL4650687 | 0.80 | CCR2 (0.51) | CCR2RECQLMAPT | |
| SCHEMBL4649881 | 0.79 | CCR2 (0.52) | CCR2RECQLMAPT | |
| SCHEMBL6303579 | 0.79 | CCR2 (0.85) | CCR2 | |
| SCHEMBL4649911 | 0.77 | CCR2 (0.52) | CCR2MAPT | |
| SCHEMBL3957310 | 0.77 | CCR2 (1.00) | CCR2 | |
| SCHEMBL6599632 | 0.76 | CCR2 (0.61) | CCR2MAPT | |
| SCHEMBL6303401 | 0.74 | CCR2 (0.74) | CCR2MAPT | |
| SCHEMBL4650663 | 0.72 | CCR2 (0.55) | CCR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904487-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006067392-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |