Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL465018

CCCC[Sn+](CCCC)CCCC.O=C([O-])C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.43
CES1 P23141 7/20 0.42
CES2 O00748 6/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
EPHX1 P07099 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2552104 0.92 FAAH (0.48) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10580960 0.86 FAAH (0.35) FAAHCES1CES2MEN1CYP1A2
Pivalate SCHEMBL6560629 0.84 CA1 (0.39) CES1CES2CA1
Bicarbonate SCHEMBL8729890 0.84 CA1 (0.46) CES1CES2CA1
Trifluoroacetic Acid SCHEMBL9810171 0.83 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10580339 0.83 FAAH (0.33) FAAHCES1CES2MEN1CYP1A2
Trichloroacetic Acid SCHEMBL911182 0.83 CA1 (0.38) CES1CES2CA1
Acetic Acid SCHEMBL23327569 0.81 CES1 (0.44) CES1CES2CA1
Oxalic Acid SCHEMBL10430586 0.81 CA1 (0.44) CES1CES2CA1
Acetic Acid SCHEMBL62981 0.81 CES1 (0.44) CES1CES2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5417757-A Vapor deposition, coating glass, window glazing PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE, (P.C.A.S.) (S.A.) (FR) 1995-05-23 US claimed
EP-1360238-B1 DATA STORAGE MEDIA CONTAINING TRANSPARENT POLYCARBONATE BLENDS SABIC INNOVATIVE PLASTICS IP (NL) 2012-01-11 EP disclosed
US-7642373-B2 Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride GE HEALTHCARE LIMITED (GB) 2010-01-05 US disclosed
EP-1697279-B1 RADICAL TRAP IN FLUORIDATION OF IODINIUM SALT GE HEALTHCARE LTD (GB) 2008-09-24 EP disclosed
US-20060292060-A1 Forming for example [18F]-dopamine or [18F]-uracil via reaction of iodonium salt precursor, where use of free radical scavenger improves yield of aryl fluoride GE HEALTHCARE LIMITED (GB) 2006-12-28 US disclosed
EP-1697279-A1 RADICAL TRAP IN FLUORIDATION OF IODINIUM SALT GE Healthcare Limited (GB) 2006-09-06 EP disclosed
US-6949279-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-09-27 US disclosed
US-6936324-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-08-30 US disclosed
US-6933034-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-08-23 US disclosed
EP-1274763-B1 PROCESS FOR REDISTRIBUTION OF POLYCARBONATE GEN ELECTRIC (US) 2005-07-20 EP disclosed
US-5417757-A Vapor deposition, coating glass, window glazing PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE, (P.C.A.S.) (S.A.) (FR) 1995-05-23 US disclosed
US-5414057-A Redistribution of organic polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1995-05-09 US disclosed
EP-0599540-A1 Polycarbonate-titanium dioxide compositions GENERAL ELECTRIC COMPANY (US) 1994-06-01 EP disclosed
EP-0595608-A1 Redistribution of organic polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1994-05-04 EP disclosed
US-5256728-A Blending in presence of catalyst GENERAL ELECTRIC COMPANY (US) 1993-10-26 US disclosed
EP-0396994-B1 PROCESS OF MAKING ELECTRICALLY CONDUCTING AND IR-REFLECTING, FLUORINE-DOPED TIN OXIDE LAYERS ON THE SURFACE OF GLASS OR GLASS-CERAMIC PRODUCTS OR OF ENAMEL COATINGS AND PREPARATION FOR APPLYING THESE LAYERS Th. Goldschmidt AG (DE) 1992-12-23 EP disclosed
US-5085805-A ELECTRICALLY CONDUCTING, IR REFLECTING, FLUORINE-DOPED TIN OXIDE ORGANIC COMPOUND TH. GOLDSCHMIDT AG 1992-02-04 US disclosed
US-5043186-A Method for the production of electrically conducting, IR reflecting, fluorine-doped tin oxide layers on the surface of objects of glass or ceramic or of enamel coatings and a preparation for the application of such layers TH. GOLDSCHMIDT AG (DE) 1991-08-27 US disclosed
EP-0396994-A1 Process of making electrically conducting and ir-reflecting, fluorine-doped tin oxide layers on the surface of glass or glass-ceramic products or of enamel coatings and preparation for applying these layers Th. Goldschmidt AG (DE) 1990-11-14 EP disclosed
EP-0338417-A2 Haze-free infrared-reflecting coated glass PPG INDUSTRIES, INC. (US) 1989-10-25 EP disclosed