SCHEMBL4650345

SCHEMBL4650345

C=CC/C=C(\C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 3/20 0.52
AKT1 P31749 1/20 0.47
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 5/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.42
AKR1C2 P52895 2/20 0.41
AKR1C3 P42330 1/20 0.41
CES1 P23141 2/20 0.40
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PTGS2 P35354 1/20 0.40
PTPN1 P18031 1/20 0.39
ERCC5 P28715 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4681821 1.00 AKR1C1 (0.52) AKR1C1AKT1KMT2AALDH1A1HPGD
SCHEMBL29088241 0.85 AKT1 (0.44) AKR1C1AKT1KMT2AALDH1A1HPGD
SCHEMBL14698519 0.79 AKR1C1 (0.55) AKR1C1AKT1KMT2AALDH1A1HPGD
SCHEMBL14698518 0.79 AKR1C1 (0.55) AKR1C1AKT1KMT2AALDH1A1HPGD
SCHEMBL8331817 0.78 AKR1C1 (0.50) AKR1C1KMT2AALDH1A1HPGDAKR1C2
SCHEMBL29009321 0.78 AKT1 (0.36) AKR1C1AKT1ALDH1A1HPGDLMNA
SCHEMBL348321 0.78 AKR1C1 (0.53) AKR1C1KMT2AALDH1A1HPGDLMNA
SCHEMBL3039305 0.78 AKR1C1 (0.53) AKR1C1KMT2AALDH1A1HPGDLMNA
SCHEMBL3039302 0.78 AKR1C1 (0.53) AKR1C1KMT2AALDH1A1HPGDLMNA
SCHEMBL5487477 0.77 CES2 (0.46) AKT1ALDH1A1HPGDLMNACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655478-B1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2017-06-14 EP claimed
EP-0860455-B1 Photocrosslinkable polymers ROLIC AG (CH) 2008-06-04 EP claimed
EP-0763552-B1 Curable, photoactive polymeric materials ROLIC AG (CH) 2001-09-19 EP claimed
EP-0860455-A2 Photocrosslinkable polymers Rolic AG (CH) 1998-08-26 EP claimed
EP-0763552-A2 Curable, photoactive polymeric materials Rolic AG (CH) 1997-03-19 EP claimed
EP-0324480-B1 Photopolymerizable compositions and elements for refractive index imaging DU PONT (US) 1994-04-13 EP claimed
EP-0860455-B1 Photocrosslinkable polymers ROLIC AG (CH) 2008-06-04 EP disclosed
EP-0763552-B1 Curable, photoactive polymeric materials ROLIC AG (CH) 2001-09-19 EP disclosed
EP-0563819-B1 Process for the treatment of leather ROEHM GMBH (DE) 1998-09-09 EP disclosed
EP-0860455-A2 Photocrosslinkable polymers Rolic AG (CH) 1998-08-26 EP disclosed
EP-0763552-A2 Curable, photoactive polymeric materials Rolic AG (CH) 1997-03-19 EP disclosed
EP-0492405-B1 Graft copolymers from acrylate and methylacrylate ROEHM GMBH (DE) 1996-09-04 EP disclosed
US-5376459-A Uniformly applying to surface graft copolymer of methacrylic esters grafted to base polymer of acrylic esters ROHM GMBH (DE) 1994-12-27 US disclosed
US-5288809-A Acrylic ester graft copolymer ROHM GMBH (DE) 1994-02-22 US disclosed
EP-0572900-A2 Coating and its use in a process for preparing multilayer coatings Herberts Gesellschaft mit beschränkter Haftung (DE) 1993-12-08 EP disclosed
US-5266645-A Moldings, low temperature strength, blocking, high cohesion ROEHM GMBH CHEMISCHE FABRIK (DE) 1993-11-30 US disclosed
EP-0563819-A1 Polymer products for treating leather RÖHM GMBH (DE) 1993-10-06 EP disclosed
EP-0492405-A1 Graft copolymers from acrylate and methylacrylate RÖHM GMBH (DE) 1992-07-01 EP disclosed