SCHEMBL5487477

SCHEMBL5487477

C=CCC=C(C(=O)O)C(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 10/20 0.46
CES1 P23141 9/20 0.46
AKT1 P31749 1/20 0.44
LMNA P02545 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
HPGD P15428 1/20 0.40
EGFR P00533 2/20 0.40
XBP1 P17861 1/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10393740 0.79 CES2 (0.52) CES2CES1LMNAALDH1A1MAPT
SCHEMBL2901224 0.79 CES2 (0.52) CES2CES1LMNAALDH1A1MAPT
SCHEMBL1135898 0.77 EP300 (0.38) LMNAALDH1A1MAPTMAPK1CYP2C19
SCHEMBL4681821 0.77 AKR1C1 (0.52) CES2CES1AKT1LMNAALDH1A1
SCHEMBL4650345 0.77 AKR1C1 (0.52) CES2CES1AKT1LMNAALDH1A1
SCHEMBL9562359 0.76 CES2 (0.41) CES2CES1AKT1LMNAALDH1A1
SCHEMBL9562364 0.76 CES2 (0.41) CES2CES1AKT1LMNAALDH1A1
SCHEMBL6679238 0.76 HPGD (0.46) CES2CES1AKT1LMNAALDH1A1
SCHEMBL9540488 0.74 CES2 (0.56) CES2CES1LMNAALDH1A1MAPT
SCHEMBL6529813 0.74 CES2 (0.56) CES2CES1LMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210378920-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2021-12-09 US claimed
US-20070089847-A1 Anti-microbial paper products having a substituted 1,2-dihydroquinoline NOVUS INTERNATIONAL, INC. (US) 2007-04-26 US claimed
WO-2007044398-A2 ANTI-MICROBIAL PAPER PRODUCTS HAVING A SUBSTITUTED 1,2-DIHYDROQUINOLINE NOVUS INTERNATIONAL INC. (US) 2007-04-19 WO claimed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US claimed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US claimed
US-11957768-B2 Wet wiper articles and methods for cleaning removable dental appliances Oral Health Technologies, LLC (US) 2024-04-16 US disclosed
US-20210378920-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2021-12-09 US disclosed
US-10881590-B2 Wet wiper articles and methods for cleaning removable dental appliances Oral Health Technologies, LLC (US) 2021-01-05 US disclosed
US-10857075-B2 Wet wiper articles and methods for cleaning removable dental appliances Oral Health Technologies, LLC (US) 2020-12-08 US disclosed
US-20180221253-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2018-08-09 US disclosed
US-20150053235-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2015-02-26 US disclosed
US-20140128304-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC (US) 2014-05-08 US disclosed
US-20050085759-A1 Pre-moistened swab apparatus DWIGHT DANA L (US) 2005-04-21 US disclosed
US-6705142-B1 Metal shaping process using a novel two phase cooling lubricant system HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-03-16 US disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
WO-2001070189-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS UNILEVER PLC (GB) 2001-09-27 WO disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-5230730-A Storage stable oil in water emulsion with emulsifiers of nonionic fatty alcohol polyethers and carboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1993-07-27 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed