SCHEMBL8631904

SCHEMBL8631904

O=S(=O)(O)c1ccc2cc(Nc3n[c]nc(F)n3)cc(S(=O)(=O)O)c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.40
CASP6 P55212 3/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP2C9 P11712 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP2C19 P33261 1/20 0.40
PTPN11 Q06124 2/20 0.37
NSD2 O96028 2/20 0.37
DUSP3 P51452 1/20 0.37
PTPN5 P54829 1/20 0.37
CASP7 P55210 1/20 0.37
ENPP2 Q13822 1/20 0.36
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA4 P22748 3/20 0.36
CA6 P23280 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7720137 0.88 ENPP2 (0.45) SNCACASP6HSD17B10CYP2C9ALDH1A1
SCHEMBL7716377 0.88 ENPP2 (0.35) CASP6HSD17B10CYP2C9ALDH1A1CYP2C19
SCHEMBL7718746 0.87 SNCA (0.55) SNCACASP6HSD17B10CYP2C9ALDH1A1
SCHEMBL7717605 0.82 CA12 (0.38) SNCACASP6PTPN11NSD2DUSP3
SCHEMBL7713024 0.81 TTR (0.37) SNCACASP6PTPN11NSD2DUSP3
SCHEMBL4650604 0.81 CA1 (0.50) SNCACA12CA1CA2CA4
SCHEMBL7717587 0.81 TIMP3 (0.39) SNCACASP6HSD17B10CYP2C9ALDH1A1
SCHEMBL4650779 0.81 SNCA (0.35) SNCACASP6HSD17B10CYP2C9ALDH1A1
SCHEMBL4650680 0.80 SNCA (0.43) SNCACASP6HSD17B10ALDH1A1PTPN11
SCHEMBL7717623 0.79 ENPP2 (0.34) CASP6PTPN11NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760193-A FOR COTTON, WOOL, POLYAMIDES; HIGH COLOR STRENGTH, COLORFASTNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-06-02 US disclosed