Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2973975 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPK1GID4NPC1RAB9A | |
| SCHEMBL4651939 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL4651065 | 0.76 | CYBB (0.30) | — | |
| SCHEMBL1453496 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL1453397 | 0.75 | RAB9A (0.37) | ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL1453390 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MAPK1GID4NPC1RAB9A | |
| SCHEMBL1451928 | 0.74 | ALDH1A1 (0.34) | ALDH1A1MAPK1GID4NPC1RAB9A | |
| SCHEMBL4650956 | 0.73 | — | — | |
| SCHEMBL2968608 | 0.73 | KDM1A (0.33) | ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL4999818 | 0.70 | NPC1 (0.31) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |