Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.46 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651949 | 1.00 | PLK1 (0.60) | PLK1MAPTPLK3PTPN1AKR1C3 | |
| SCHEMBL4651954 | 1.00 | PLK1 (0.60) | PLK1MAPTPLK3PTPN1AKR1C3 | |
| SCHEMBL4651842 | 0.85 | MAPT (0.48) | PLK1MAPTPLK3AKR1C3AKR1C2 | |
| SCHEMBL4651616 | 0.84 | CXCR2 (0.51) | MAPTPTPN1ALDH1A1KDM4ECXCR2 | |
| SCHEMBL4652888 | 0.84 | CXCR2 (0.51) | MAPTPTPN1ALDH1A1KDM4ECXCR2 | |
| SCHEMBL4651710 | 0.84 | CXCR2 (0.51) | MAPTPTPN1ALDH1A1KDM4ECXCR2 | |
| SCHEMBL4651959 | 0.84 | PLK1 (0.61) | PLK1MAPTPLK3PTPN1AKR1C3 | |
| SCHEMBL4651952 | 0.84 | PLK1 (0.61) | PLK1MAPTPLK3PTPN1AKR1C3 | |
| SCHEMBL4650949 | 0.84 | PLK1 (0.61) | PLK1MAPTPLK3PTPN1AKR1C3 | |
| SCHEMBL9211107 | 0.81 | PRSS12 (0.50) | PLK1MAPTAKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |