Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 8/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651952 | 1.00 | PLK1 (0.61) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4651959 | 1.00 | PLK1 (0.61) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4651844 | 0.85 | PLK1 (0.46) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4651949 | 0.84 | PLK1 (0.60) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4651954 | 0.84 | PLK1 (0.60) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4650948 | 0.84 | PLK1 (0.60) | PLK1PTPN1PLK3SMN1; SMN2MEN1 | |
| SCHEMBL4652887 | 0.83 | TSHR (0.48) | MEN1KMT2APTPN11ALDH1A1LMNA | |
| SCHEMBL4651612 | 0.83 | TSHR (0.48) | MEN1KMT2APTPN11ALDH1A1LMNA | |
| SCHEMBL4651707 | 0.83 | TSHR (0.48) | MEN1KMT2APTPN11ALDH1A1LMNA | |
| SCHEMBL4651631 | 0.78 | LMNA (0.46) | MEN1KMT2AHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |