SCHEMBL4650997

SCHEMBL4650997

O=S(=O)(O)c1ccc(S(=O)(=O)O)c(Nc2n[c]nc(Cl)n2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FUT8 Q9BYC5 1/20 0.39
CHAT P28329 4/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
USP2 O75604 1/20 0.37
APEX1 P27695 1/20 0.37
HPGDS O60760 1/20 0.35
CA12 O43570 6/20 0.33
CA1 P00915 6/20 0.33
CA2 P00918 6/20 0.33
CA9 Q16790 6/20 0.33
CA14 Q9ULX7 3/20 0.33
SNCA P37840 2/20 0.33
CASP6 P55212 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
P2RY2 P41231 1/20 0.32
P2RY12 Q9H244 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9462489 0.90 CHAT (0.44) FUT8CHATENPP3ENPP1USP2
SCHEMBL4104068 0.85 CA12 (0.47) FUT8CHATENPP3ENPP1USP2
SCHEMBL4650779 0.85 SNCA (0.35) FUT8CHATENPP3ENPP1CA12
SCHEMBL4650519 0.83 HPGDS (0.45) FUT8CHATENPP3ENPP1USP2
SCHEMBL18902955 0.81 TNNI3K (0.40) FUT8CHATENPP3ENPP1USP2
SCHEMBL10710561 0.80 APEX1 (0.44) FUT8CHATENPP3ENPP1APEX1
SCHEMBL4651485 0.80 CA9 (0.50) CHATUSP2APEX1CA12CA1
SCHEMBL14087149 0.80 CHAT (0.41) FUT8CHATENPP3ENPP1USP2
SCHEMBL4650630 0.79 CHAT (0.46) CHATENPP3ENPP1CA12CA1
SCHEMBL12421835 0.77 LMNA (0.45) FUT8CHATENPP3ENPP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013018057-A2 FIBRE REACTIVE BISAZO REACTIVE COLORANTS, MIXTURES OF REACTIVE COLORANTS, PRODUCTION AND USE THEREOF COLOURTEX INDUSTRIES LIMITED (IN) 2013-02-07 WO disclosed
EP-1397438-B1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-09-10 EP disclosed
US-7060114-B2 Dye mixtures of fiber-reactive azo dyes and the use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-06-13 US disclosed
EP-1397439-B1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2005-11-16 EP disclosed
US-6962611-B2 Dye mixtures of fiber-reactive azodyes and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-11-08 US disclosed
US-6946006-B2 Black dye mixtures of fiber-reactive AZO dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-09-20 US disclosed
US-20040148714-A1 Dye mixtures of fiber-reactive azodyes and the use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2004-08-05 US disclosed
US-20040139567-A1 Dye mixtures of fiber-reactive azodyes and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2004-07-22 US disclosed
EP-1397437-A2 BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-03-17 EP disclosed
EP-1397439-A2 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND USE THEREOF DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-03-17 EP disclosed
WO-2002098989-A1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-12-12 WO disclosed
WO-2002098986-A2 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-12-12 WO disclosed
WO-2002098988-A2 BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-12-12 WO disclosed
EP-0773264-B1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-10-10 EP disclosed
US-5944854-A LEUCO DYES DYSTAR TEXTILFARBEN GMBH & CO. (DE) 1999-08-31 US disclosed
US-5831039-A Fiber reactive polyazo dyes containing two urea groups DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-03 US disclosed
EP-0872523-A2 Fiber-reactive azo dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-10-21 EP disclosed
US-5696258-A REDUCING TO LEUCO FORM; REOXIDATION DYSTAR TEXTILFARBEN GMBH (DE) 1997-12-09 US disclosed
EP-0773264-A1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-05-14 EP disclosed
US-5207801-A Colorfastness CIBA-GEIGY CORPORATION (US) 1993-05-04 US disclosed