Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649567 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CNR2MITF | |
| SCHEMBL1415727 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL27505917 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL6936570 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL15901735 | 0.78 | CHIT1 (0.43) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL15901734 | 0.78 | CHIT1 (0.43) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL4473540 | 0.76 | CNR2 (0.57) | CNR2 | |
| SCHEMBL4473536 | 0.76 | CNR2 (0.57) | CNR2 | |
| SCHEMBL4461953 | 0.76 | CNR2 (0.59) | CNR2 | |
| SCHEMBL4651287 | 0.76 | CNR2 (0.64) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |