Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27505917 | 1.00 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3MITFSIGMAR1 | |
| SCHEMBL1415727 | 1.00 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3MITFSIGMAR1 | |
| Pyridine SCHEMBL28173600 | 0.92 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3MITFCA1 | |
| SCHEMBL27469280 | 0.86 | KMT2A (0.50) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL7826769 | 0.86 | KMT2A (0.50) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL4649567 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MITFCA1 | |
| SCHEMBL23058169 | 0.86 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MITFSIGMAR1 | |
| SCHEMBL28861068 | 0.86 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3MITFTDP1 | |
| SCHEMBL1738860 | 0.86 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3MITFSIGMAR1 | |
| SCHEMBL2080509 | 0.86 | SIGMAR1 (0.53) | SLC6A2SLC6A4SLC6A3MITFSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127488-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2003-11-12 | — | — | CN | disclosed |
| EP-0907643-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2003-01-15 | — | — | EP | disclosed |
| US-5919777-A | PIPERAZINE DERIVATIVES USEFUL FOR TREATING MEDICAL DISORDERS RESULTING FROM A GROWTH HORMONE DEFIENCY | NOVO NORDISK A/S (DK) | 1999-07-06 | — | — | US | disclosed |
| CN-1216537-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-05-12 | — | — | CN | disclosed |
| EP-0907643-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997040023-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-10-30 | — | — | WO | disclosed |