Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387054 | 0.76 | KDM4E (0.39) | KDM4EPKMGAAMAPT | |
| SCHEMBL251287 | 0.76 | KDM4E (0.39) | KDM4EPKMGAAMAPT | |
| SCHEMBL28056042 | 0.74 | KDM4E (0.38) | KDM4EPKMGAAMAPT | |
| SCHEMBL27414073 | 0.74 | KDM4E (0.38) | KDM4EPKMGAAMAPT | |
| Ammonia Solution, Strong SCHEMBL7086115 | 0.74 | KDM4E (0.38) | KDM4EPKMGAAMAPT | |
| SCHEMBL10925551 | 0.67 | KDM4E (0.47) | KDM4EPKMGAAMAPT | |
| SCHEMBL10919330 | 0.67 | KDM4E (0.39) | KDM4EPKMGAAMAPT | |
| SCHEMBL27390499 | 0.65 | KDM4E (0.46) | KDM4EPKMGAAMAPT | |
| SCHEMBL6631795 | 0.65 | KDM4E (0.32) | KDM4EPKM | |
| SCHEMBL28239121 | 0.64 | KDM4E (0.34) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451937-B1 | BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST | SHELL OIL COMPANY | 2002-09-17 | — | — | US | claimed |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | SHELL OIL COMPANY | 2001-11-08 | — | — | US | claimed |
| EP-1500659-B1 | Selective, catalytic, thermal functionalization of secondary or aromatic C-H bonds in cyclic hydrocarbons | SHELL INT RESEARCH (NL) | 2008-09-24 | — | — | EP | disclosed |
| EP-1268490-B1 | SELECTIVE, CATALYTIC, THERMAL FUNCTIONALIZATION OF SECONDARY OR AROMATIC C-H BONDS IN CYCLIC HYDROCARBONS | SHELL INT RESEARCH (NL) | 2005-01-26 | — | — | EP | disclosed |
| EP-1500659-A1 | Selective, catalytic, thermal functionalization of secondary or aromatic C-H bonds in cyclic hydrocarbons | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2005-01-26 | — | — | EP | disclosed |
| EP-1259517-B1 | SELECTIVE, CATALYTIC, AND THERMALLY INDUCED FUNCTIONALIZATION OF PRIMARY C-H BONDS IN HYDROCARBONS | SHELL INT RESEARCH (NL) | 2003-09-17 | — | — | EP | disclosed |
| EP-1268490-A1 | SELECTIVE, CATALYTIC, THERMAL FUNCTIONALIZATION OF SECONDARY OR AROMATIC C-H BONDS IN CYCLIC HYDROCARBONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2003-01-02 | — | — | EP | disclosed |
| US-6451937-B1 | BY THERMALLY REACTING A FUNCTIONALIZING REAGENT AND THE HYDROCARBON IN THE PRESENCE OF A TRANSITION METAL COORDINATION CATALYST | SHELL OIL COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | SHELL OIL COMPANY | 2001-11-08 | — | — | US | disclosed |
| WO-2001064688-A1 | SELECTIVE, CATALYTIC, THERMAL FUNCTIONALIZATION OF SECONDARY OR AROMATIC C-H CYCLIC HYDROCARBON BONDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | AHR, PAH, HRH3 | KDM4E 2533/4885PKM 2867/4885GAA 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.