Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251287 | 0.98 | KDM4E (0.39) | KDM4EPKMOXTRGAAMAPT | |
| SCHEMBL29387054 | 0.98 | KDM4E (0.39) | KDM4EPKMOXTRGAAMAPT | |
| SCHEMBL28056042 | 0.95 | KDM4E (0.38) | KDM4EPKMOXTRGAAMAPT | |
| SCHEMBL27414073 | 0.95 | KDM4E (0.38) | KDM4EPKMOXTRGAAMAPT | |
| Oxalic Acid SCHEMBL27277403 | 0.88 | KDM4E (0.36) | KDM4EPKMOXTR | |
| SCHEMBL27932895 | 0.77 | OXTR (0.33) | KDM4EPKMOXTRGAAMAPT | |
| SCHEMBL19933057 | 0.76 | OXTR (0.36) | KDM4EPKMOXTR | |
| SCHEMBL8861340 | 0.74 | OXTR (0.33) | KDM4EPKMOXTRGAAMAPT | |
| SCHEMBL4651302 | 0.74 | KDM4E (0.37) | KDM4EPKMGAAMAPT | |
| SCHEMBL5090884 | 0.74 | OXTR (0.33) | KDM4EPKMOXTRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114609-C | 3-heteroatom substituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-07-16 | — | — | CN | disclosed |
| EP-1276739-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | Bristol-Myers Squibb Company (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081340-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-01 | — | — | WO | disclosed |
| CN-1230190-A | 3-heteroatom sustituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | CN | disclosed |