SCHEMBL4652250

SCHEMBL4652250

CC1=CC(C)(O)OC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3232301 0.75
SCHEMBL3750812 0.68
SCHEMBL3239326 0.65 LMNA (0.30)
SCHEMBL3232288 0.64 POLB (0.32)
SCHEMBL3234662 0.62 POLB (0.34)
SCHEMBL11800450 0.62
SCHEMBL6511417 0.62 ALDH1A1 (0.33)
SCHEMBL3237199 0.62 AKT1 (0.32)
SCHEMBL10705052 0.62
SCHEMBL19873015 0.59 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230406821-A1 STRIGOLACTONE DERIVATIVES Plant Response, Inc. 2023-12-21 US disclosed
US-11787763-B2 Strigolactone derivauves Plant Response, Inc. (US) 2023-10-17 US disclosed
US-11787763-B2 Strigolactone derivauves Plant Response, Inc. (US) 2023-10-17 US disclosed
US-11787763-B2 Strigolactone derivauves Plant Response, Inc. (US) 2023-10-17 US disclosed
US-20200354316-A1 STRIGOLACTONE DERIVATIVES KOCH BIOLOGICAL SOLUTIONS, LLC 2020-11-12 US disclosed
US-20200354316-A1 STRIGOLACTONE DERIVATIVES KOCH BIOLOGICAL SOLUTIONS, LLC 2020-11-12 US disclosed
CN-103420959-B Method for synthesizing hydroxyl butenolide and congeners thereof BEIJING INST FASHION TECH 2015-04-15 CN disclosed
CN-103420959-A Method for synthesizing hydroxyl butenolide and congeners thereof BEIJING INST FASHION TECH 2013-12-04 CN disclosed
EP-1294705-B1 SYNTHESIS OF CYCLIC COMPOUNDS BIOSIGNAL LTD (AU) 2008-09-10 EP disclosed
CN-1688543-A Furanone derivatives and methods of making same BIOSIGNAL PTY LTD (AU) 2005-10-26 CN disclosed
US-6958145-B2 Synthesis of cyclic compounds UNISEARCH LIMITED (AU) 2005-10-25 US disclosed
US-20050215772-A1 Furanone derivatives and methods of making same BIOSIGNAL LIMITED (AT) 2005-09-29 US disclosed
EP-1539692-A4 FURANONE DERIVATIVES AND METHODS OF MAKING SAME BIOSIGNAL LTD (AU) 2005-08-24 EP disclosed
EP-1539692-A1 FURANONE DERIVATIVES AND METHODS OF MAKING SAME Biosignal Limited (AU) 2005-06-15 EP disclosed
EP-1294705-A4 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LTD (AU) 2005-02-09 EP disclosed
US-20040110966-A1 Synthesis of cyclic compounds UNISEARCH LIMITED (AU) 2004-06-10 US disclosed
WO-2004016588-A1 FURANONE DERIVATIVES AND METHODS OF MAKING SAME BIOSIGNAL LIMITED (AU) 2004-02-26 WO disclosed
EP-1294705-A1 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LIMITED (AU) 2003-03-26 EP disclosed
WO-2002000639-A1 SYNTHESIS OF CYCLIC COMPOUNDS UNISEARCH LIMITED (AU) 2002-01-03 WO disclosed