SCHEMBL465245

SCHEMBL465245

c1ccc(CC2CO2)nc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
LIN28A Q9H9Z2 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
HRH3 Q9Y5N1 1/20 0.40
LMNA P02545 1/20 0.39
KDM1A O60341 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28440523 0.98 HRH1 (0.42) HRH1TDP1SMN1; SMN2MAPTLIN28A
SCHEMBL2752484 0.80 POLB (0.51) TDP1SMN1; SMN2MAPTMEN1ALDH1A1
SCHEMBL2128245 0.79 POLB (0.47) SMN1; SMN2MAPTMEN1ALDH1A1PKM
SCHEMBL30418424 0.78 HRH1 (0.42) HRH1TDP1SMN1; SMN2MAPTLIN28A
SCHEMBL16606327 0.77 MAPT (0.58) HRH1TDP1SMN1; SMN2MAPTLIN28A
SCHEMBL9869371 0.77 TDP1 (0.47) HRH1TDP1SMN1; SMN2MEN1ALDH1A1
SCHEMBL2721877 0.77 HRH3 (0.33) HRH1SMN1; SMN2MEN1ALDH1A1KMT2A
SCHEMBL5338566 0.77 SLC6A2 (0.48) HRH1
SCHEMBL1515445 0.75 SMN1; SMN2 (0.48) HRH1TDP1SMN1; SMN2MAPTLIN28A
SCHEMBL18919009 0.74 ALDH1A1 (0.35) TDP1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440127-B1 FAST-CURE PRE-PREG CYTEC IND INC (US) 2023-10-11 EP claimed
EP-3302945-B1 AUTOMATED PROCESS FOR CONVEYING PREPREGS WITH THE PREPREG COMPRISING A DRY-FIBRE VEIL SURFACE LAYER AND PREPREG CYTEC IND INC (US) 2020-08-05 EP claimed
EP-2900726-B1 RESIN COMPOSITION AND COMPOSITE STRUCTURE CONTAINING RESIN HEXCEL COMPOSITES LTD (GB) 2020-04-08 EP claimed
EP-2084205-B1 COMPOSITE MATERIALS WITH IMPROVED PERFORMANCE HEXCEL COMPOSITES LTD (GB) 2011-11-23 EP claimed
CN-112812259-A Light-cured adhesive for additive manufacturing and synthetic method thereof 南京理工大学 2021-05-18 CN disclosed
CN-111099949-B Catalytic cracking method 中国石油化工股份有限公司 2021-04-06 CN disclosed
CN-111099949-A Catalytic cracking method 中国石油化工股份有限公司 2020-05-05 CN disclosed
CN-105729818-A IMPROVEMENTS IN OR RELATING TO LAMINATES 赫克赛尔控股有限责任公司 2016-07-06 CN disclosed
CN-105585820-A Prepregs for mouldings of reduced void content HEXCEL COMPOSITES LTD 2016-05-18 CN disclosed
CN-105431287-A Improvements in or relating to fibre reinforced composites HEXCEL COMPOSITES LTD 2016-03-23 CN disclosed
CN-105324417-A Improvements in or relating to epoxy resin formulations HEXCEL COMPOSITES LTD 2016-02-10 CN disclosed
CN-105209528-A Fire retardant epoxy resin formulations and their use HEXCEL COMPOSITES LTD 2015-12-30 CN disclosed
CN-105073402-A Composite material HEXCEL COMPOSITES LTD 2015-11-18 CN disclosed
CN-101755021-B Adhesion promoting layer for composite assemblies HEXCEL COMPOSITES LTD 2014-12-31 CN disclosed
CN-101522750-B Composite materials with improved performance HEXCEL COMPOSITES LTD 2013-02-06 CN disclosed
CN-101755021-A Adhesion promoting layer for composite assemblies HEXCEL COMPOSITES LTD 2010-06-23 CN disclosed
US-4299924-A IMPROVED RIGIDITY, HEAT RESISTANCE, AND IMPACT RESISTANCE TOYOTA JIDOSHA KOGYO KABUSHIKI KAISHA (JP) 1981-11-10 US disclosed
US-3931065-A POLYURETHANE-MODIFIED POLYISOCYANURATE FOAM AND A METHOD FOR THE PREPARATION THEREOF NISSHIN BOSEKI KABUSHIKI KAISHA (JA) 1976-01-06 US disclosed