SCHEMBL465252

SCHEMBL465252

CN(C)c1ccc(C=CCCCN)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.50
RELA Q04206 1/20 0.48
MAPT P10636 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CASP1 P29466 2/20 0.47
HBB P68871 2/20 0.47
ALDH1A1 P00352 2/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.47
BRCA1 P38398 1/20 0.47
CASP7 P55210 1/20 0.47
ALPG P10696 1/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.47
GFER P55789 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NPC1 O15118 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11587602 0.84 TNNC1 (0.38)
SCHEMBL28276321 0.84 KDM4A (0.55) APPRELAMAPTMEN1KMT2A
SCHEMBL8715886 0.82 APP (0.56) APPRELAMAPTMEN1KMT2A
SCHEMBL2769282 0.81 APP (0.57) APPRELAMAPTMEN1KMT2A
SCHEMBL2769283 0.81 APP (0.57) APPRELAMAPTMEN1KMT2A
SCHEMBL23303386 0.81 KDM4A (0.60) APPRELAMAPTMEN1KMT2A
SCHEMBL23303385 0.81 KDM4A (0.60) APPRELAMAPTMEN1KMT2A
SCHEMBL28758484 0.81 CYP2A6 (0.50) APPRELAMAPTMEN1KMT2A
SCHEMBL25000571 0.79 APP (0.55) APPRELAMAPTMEN1KMT2A
SCHEMBL31414181 0.77 RELA (0.56) APPRELAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415907-B2 Rubber composition and run-flat tire BRIDGESTONE CORPORATION (JP) 2025-09-16 US disclosed
CN-114502629-B Safety tyre 株式会社普利司通 2024-12-24 CN disclosed
EP-3725839-B1 RUBBER COMPOSITION AND TIRE USING SAME BRIDGESTONE CORP (JP) 2024-10-30 EP disclosed
CN-111492000-B Rubber composition and tire using same 株式会社普利司通 2023-02-17 CN disclosed
US-20220363093-A1 RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-11-17 US disclosed
US-20220348746-A1 RUBBER COMPOSITION AND RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-11-03 US disclosed
EP-4039502-A1 RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-08-10 EP disclosed
EP-4039503-A1 RUBBER COMPOSITION AND RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-08-10 EP disclosed
EP-3725839-A1 RUBBER COMPOSITION AND TIRE USING SAME Bridgestone Corporation (JP) 2020-10-21 EP disclosed
US-20200299427-A1 RUBBER COMPOSITION AND TIRE USING SAME BRIDGESTONE CORPORATION (JP) 2020-09-24 US disclosed
EP-2289992-A1 RUBBER COMPOSITION AND TIRE USING THE SAME Bridgestone Corporation (JP) 2011-03-02 EP disclosed
EP-2289710-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-03-02 EP disclosed
EP-2287015-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-02-23 EP disclosed
US-20100006199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORPORATION (JP) 2010-01-14 US disclosed
EP-2060604-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME Bridgestone Corporation (JP) 2009-05-20 EP disclosed
US-20080289740-A1 Rubber Composition and Pneumatic Tire Using Same BRIDGESTONE CORPORATION (JP) 2008-11-27 US disclosed
EP-1854838-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME Bridgestone Corporation (JP) 2007-11-14 EP disclosed
US-20060272760-A1 Pneumatic tire BRIDGESTONE CORPORATION 2006-12-07 US disclosed
EP-1297974-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2003-04-02 EP disclosed
US-20030015272-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-23 US disclosed