SCHEMBL465261

SCHEMBL465261

C=CC(C)CC=CCCCC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LTB4R Q15722 1/20 0.38
ABCG2 Q9UNQ0 2/20 0.36
CACNA2D1 P54289 1/20 0.36
CACNB2 Q08289 1/20 0.36
CACNA1C Q13936 1/20 0.36
FAAH O00519 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
PTGS1 P23219 1/20 0.35
PPARG P37231 1/20 0.35
OPRK1 P41145 1/20 0.35
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522419 0.94 FAAH (0.43) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL6240110 0.92 FAAH (0.47) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL6787815 0.92 FAAH (0.47) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL11568534 0.92 FAAH (0.47) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL11599037 0.92 FAAH (0.47) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL11365466 0.92 FAAH (0.47) TSHRLTB4RABCG2CACNA2D1CACNB2
SCHEMBL599411 0.86 TSHR (0.38) TSHRLTB4R
SCHEMBL687188 0.83 TSHR (0.42) TSHRALDH1A1ABCG2CACNA2D1CACNB2
SCHEMBL1535145 0.83 TSHR (0.42) TSHRALDH1A1ABCG2CACNA2D1CACNB2
SCHEMBL7287301 0.78 LTB4R (0.44) TSHRALDH1A1LTB4RFAAHF7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2070985-B1 THERMOPLASTIC RESIN COMPOSITION AND RESIN MOLDED ARTICLE TECHNO POLYMER CO LTD (JP) 2011-07-20 EP disclosed
CN-1093864-C Polypropylene and biaxially oriented film produced with said polypropylene SUITOMO CHEMICAL CO LTD (JP) 2002-11-06 CN disclosed
EP-1153068-A1 POLYOLEFINS AS NUCLEATING AGENTS FOR FOAMED THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 2001-11-14 EP disclosed
WO-2000039204-A1 POLYOLEFINS AS NUCLEATING AGENTS FOR FOAMED THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 2000-07-06 WO disclosed
CN-1053199-C Process for producing olefin polymer and olefin polymerization catalyst SUMITOMO CHEMICAL CO (JP) 2000-06-07 CN disclosed
CN-1183418-A Polypropylene and biaxially oriented film produced with said polypropylene SUMITOMO CHEMICAL CO (JP) 1998-06-03 CN disclosed
EP-0813623-A2 POLYARYLENE SULFIDE MELT BLOWING METHODS AND PRODUCTS Pall Corporation (US) 1997-12-29 EP disclosed
WO-1997021857-A2 POLYARYLENE SULFIDE MELT BLOWING METHODS AND PRODUCTS PALL CORPORATION (US) 1997-06-19 WO disclosed
CN-1107163-A Process for preparing polyolefin, catalyst for olefin polymerization and polypropylene prepared therefrom SUMITOMO CHEMICAL CO (JP) 1995-08-23 CN disclosed
US-5237013-A A prepolymerized polyolefin in mixture, defect-free film IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1993-08-17 US disclosed
EP-0419874-A2 Composition of polybutene-1 and process for preparing same IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-04-03 EP disclosed
EP-0313838-A2 Cycloolefin polymers obtained from resinous monomers THE B.F. GOODRICH COMPANY (US) 1989-05-03 EP disclosed