Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAD | Q92934 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651842 | 0.86 | MAPT (0.48) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4652909 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4651616 | 0.81 | CXCR2 (0.51) | ALDH1A1PTPN2PTPN1LMNAKMT2A | |
| SCHEMBL15697532 | 0.79 | PTPN2 (0.56) | ALDH1A1PTPN2PTPN1LMNAKMT2A | |
| SCHEMBL1401911 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL29362343 | 0.76 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL29281966 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4633961 | 0.75 | CXCR2 (0.50) | ALDH1A1PTPN2PTPN1LMNAKMT2A | |
| SCHEMBL25274266 | 0.74 | PTPN2 (0.53) | ALDH1A1PTPN2PTPN1LMNAKMT2A | |
| SCHEMBL11844844 | 0.74 | PTPN2 (0.60) | ALDH1A1PTPN2PTPN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |