Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651844 | 0.85 | PLK1 (0.46) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4652910 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL4651707 | 0.80 | TSHR (0.48) | ALDH1A1CYP3A4LMNATSHRTDP1 | |
| SCHEMBL4652887 | 0.80 | TSHR (0.48) | ALDH1A1CYP3A4LMNATSHRTDP1 | |
| SCHEMBL4651612 | 0.80 | TSHR (0.48) | ALDH1A1CYP3A4LMNATSHRTDP1 | |
| SCHEMBL31750409 | 0.75 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL128501 | 0.75 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL31751235 | 0.75 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL30343699 | 0.75 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL29281966 | 0.73 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |