Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653050 | 0.87 | — | — | |
| SCHEMBL18729651 | 0.75 | CES2 (0.38) | CES2CES1NOS2MGLLHDAC8 | |
| SCHEMBL4654430 | 0.73 | SHBG (0.37) | CES2CES1GAATSHR | |
| SCHEMBL1911562 | 0.71 | CES2 (0.46) | CES2CES1GAAHDAC8HDAC6 | |
| SCHEMBL11129315 | 0.71 | CES2 (0.39) | CES2CES1NOS2MGLLHDAC8 | |
| SCHEMBL2600359 | 0.69 | CES2 (0.50) | CES2CES1GAAHDAC8HDAC6 | |
| SCHEMBL16674533 | 0.69 | CES2 (0.50) | CES2CES1GAAHDAC8HDAC6 | |
| SCHEMBL10895308 | 0.69 | CES2 (0.38) | CES2CES1NOS2MGLLHDAC8 | |
| SCHEMBL1228934 | 0.69 | CES2 (0.50) | CES2CES1GAAHDAC8HDAC6 | |
| SCHEMBL22861598 | 0.66 | CES2 (0.59) | CES2CES1GAAHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986598-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | Merck Patent GmbH (DE) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093252-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | MERCK PATENT GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |