Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.53 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.53 |
| ▸ | NPY4R | P50391 | 4/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653106 | 0.87 | TP53 (0.44) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL650331 | 0.85 | NPY1R (0.72) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL31652661 | 0.85 | NPY1R (0.50) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL31652535 | 0.84 | NPY1R (0.54) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL31652720 | 0.83 | NPY1R (0.52) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL31652820 | 0.83 | NPY1R (0.54) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL13449162 | 0.83 | TP53 (0.46) | — | |
| SCHEMBL9202898 | 0.82 | NPY1R (0.40) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL13450342 | 0.82 | NPY4R (0.45) | NPY1RNPY5RNPY4RNPY2R | |
| SCHEMBL31652623 | 0.82 | NPY1R (0.53) | NPY1RNPY5RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |