Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 10/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | NPY4R | P50391 | 3/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
| ▸ | NPY2R | P49146 | 2/20 | 0.40 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202898 | 0.87 | NPY1R (0.40) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4653101 | 0.87 | NPY1R (0.54) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL5057899 | 0.85 | NPY1R (0.53) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8124229 | 0.85 | NPY1R (0.41) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL1388761 | 0.83 | NPY1R (0.51) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8111984 | 0.78 | NPY1R (0.56) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL1388704 | 0.77 | TLR2 (0.42) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL4652031 | 0.77 | NPY1R (0.48) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL1388313 | 0.77 | NPY1R (0.44) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL8112566 | 0.75 | TP53 (0.40) | TP53CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |