Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HTR1E | P28566 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450342 | 0.90 | NPY4R (0.45) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4653101 | 0.83 | NPY1R (0.54) | — | |
| SCHEMBL8529342 | 0.80 | NPY1R (0.51) | — | |
| SCHEMBL30019494 | 0.78 | FURIN (0.43) | — | |
| SCHEMBL29531971 | 0.76 | NPY4R (0.51) | — | |
| SCHEMBL30903436 | 0.76 | NPY4R (0.51) | — | |
| SCHEMBL9829773 | 0.75 | HTR1E (0.64) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL13448837 | 0.75 | NPY4R (0.52) | — | |
| SCHEMBL30437446 | 0.75 | NPY4R (0.52) | — | |
| SCHEMBL30631962 | 0.75 | C3AR1 (0.46) | PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166018-A2 | Antibody binding affinity ligands | Novo Nordisk A/S (DK) | 2010-03-24 | — | — | EP | disclosed |