Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 18/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.60 |
| ▸ | NPY4R | P50391 | 3/20 | 0.60 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.59 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751683 | 0.93 | NPY1R (0.62) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL6899864 | 0.92 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7059807 | 0.92 | NPY1R (0.71) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7753036 | 0.91 | NPY1R (0.59) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL4651828 | 0.91 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL650331 | 0.91 | NPY1R (0.72) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7746012 | 0.91 | NPY1R (0.61) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL4653108 | 0.90 | NPY1R (0.60) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7751915 | 0.90 | NPY1R (0.60) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 | |
| SCHEMBL7039837 | 0.90 | NPY1R (0.60) | NPY1RNPY5RNPY4RNPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007077333-A2 | USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS | L'OREAL (FR) | 2007-07-12 | — | — | WO | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |