Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16909017 | 0.96 | SIRT5 (0.57) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL5840063 | 0.96 | SIRT5 (0.57) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL16909018 | 0.96 | SIRT5 (0.57) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL25206530 | 0.92 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL25206531 | 0.92 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL19820014 | 0.90 | CTSS (0.54) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL29528903 | 0.90 | SIRT5 (0.55) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL25463114 | 0.89 | SIRT5 (0.52) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL22507116 | 0.89 | CTSS (0.57) | CTSSCTSKSIRT5CAPN1ITGB3 | |
| SCHEMBL29071588 | 0.89 | SIRT5 (0.56) | CTSSCTSKSIRT5CAPN1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991525-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | Serenex, Inc. (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2007101156-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2007-09-07 | — | — | WO | claimed |