SCHEMBL465346

SCHEMBL465346

C=CC(=O)OCC1C(C)CC(C)CC1C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.40
HPGD P15428 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
THRB P10828 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23494392 0.85 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23494077 0.84 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14141094 0.81 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL10150647 0.79 TSHR (0.44) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL465414 0.78 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23493891 0.78 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11240136 0.77 NLRP3 (0.38) TSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL24856771 0.76 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL465417 0.75 ALDH1A1 (0.51) TSHRALDH1A1CYP3A4THRB
SCHEMBL23493908 0.74 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023286634-A1 LAYERED PRODUCT 帝人株式会社 2023-01-19 WO disclosed
EP-1995056-B1 MULTILAYER BODY TEIJIN CHEMICALS LTD (JP) 2016-08-17 EP disclosed
US-8859099-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-10-14 US disclosed
US-8765891-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2014-07-01 US disclosed
US-20130165570-A1 LAMINATE OF AN ACRYLIC RESIN COMPOSITION LAYER CONTAINING TRIAZINE BASED ULTRA-VIOLET COMPOUNDS AND AN ORGANOSILOXANE RESIN COMPOSITION LAYER TEIJIN CHEMICALS, LTD. (JP) 2013-06-27 US disclosed
US-20130165557-A1 LAMINATE OF AN ACRYLIC RESIN COMPOSITION LAYER CONTAINING TRIAZINE BASED ULTRA-VIOLET COMPOUNDS AND AN ORGANOSILOXANE RESIN COMPOSITION LAYER TEIJIN CHEMICALS, LTD. (JP) 2013-06-27 US disclosed
US-8404349-B2 Laminate of an acrylic resin composition layer containing triazine based ultra-violet compounds and an organosiloxane resin composition layer TEIJIN CHEMICALS, LTD. (JP) 2013-03-26 US disclosed
EP-2511093-A1 Multilayer body Teijin Chemicals, Ltd. (JP) 2012-10-17 EP disclosed
WO-2012018202-A3 ELECTRIC VEHICLE (주)브이이엔에스 (KR) 2012-05-10 WO disclosed
EP-2204413-B1 POLYCARBONATE RESIN LAMINATE TEIJIN CHEMICALS LTD (JP) 2011-11-30 EP disclosed
US-20100255293-A1 POLYCARBONATE RESIN LAMINATE TEIJIN CHEMICALS, LTD. (JP) 2010-10-07 US disclosed
EP-2204413-A1 POLYCARBONATE RESIN LAMINATE Teijin Chemicals, Ltd. (JP) 2010-07-07 EP disclosed
US-20090104447-A1 Laminate TEIJIN CHEMICALS, LTD. (JP) 2009-04-23 US disclosed
EP-1995056-A1 MULTILAYER BODY Teijin Chemicals, Ltd. (JP) 2008-11-26 EP disclosed