SCHEMBL465382

SCHEMBL465382

CCC(O)N(CCN(C(O)CC)C(O)CC)C(O)CC

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3835104 0.89 CA12 (0.36) TSHR
SCHEMBL465474 0.88 TSHR (0.35) TSHR
SCHEMBL2845509 0.87 TSHR (0.30) TSHR
SCHEMBL11173115 0.85 MAPT (0.36) TSHR
SCHEMBL522380 0.83 CA12 (0.34) TSHR
SCHEMBL7869148 0.83 TSHR (0.32) TSHR
SCHEMBL2849370 0.83 TSHR (0.32) TSHR
SCHEMBL2843563 0.83
SCHEMBL3218807 0.81 DNM1 (0.40) TSHR
SCHEMBL465304 0.80 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4368198-A1 COMPOSITION FOR DELIVERING A PROTEIN OR A POLYPEPTIDE TO A EUKARYOTIC CELL Klinikum der Universität München (DE) 2024-05-15 EP claimed
US-11077205-B2 Synthetic compound for improving efficiency of transfection KLINIKUM DER UNIVERSITÄT MÜNCHEN (DE) 2021-08-03 US claimed
US-20190083654-A1 Synthetic Compound for Improving Efficiency of Transfection KLINIKUM DER UNIVERSITAET MUENCHEN (DE) 2019-03-21 US claimed
US-10202484-B2 Shape-memory-self-healing polymers (SMSHPS) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2019-02-12 US claimed
EP-3436045-A1 SYNTHETIC COMPOUND FOR IMPROVING EFFICIENCY OF TRANSFECTION Klinikum der Universität München (DE) 2019-02-06 EP claimed
WO-2017167870-A1 SYNTHETIC COMPOUND FOR IMPROVING EFFICIENCY OF TRANSFECTION KLINIKUM DER UNIVERSITÄT MÜNCHEN (DE) 2017-10-05 WO claimed
EP-3225246-A1 SYNTHETIC COMPOUND FOR IMPROVING EFFICIENCY OF TRANSFECTION Klinikum der Universität München (DE) 2017-10-04 EP claimed
US-20170008998-A1 Shape-Memory-Self-Healing Polymers (SMSHPS) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2017-01-12 US claimed
EP-0633300-B1 Viscosity-stable high solids rosin-phenolic resin solutions WESTVACO CORP (US) 1997-05-21 EP claimed
EP-0688328-B1 NOVEL METHOD FOR PREPARING SLIGHTLY COLOURED ALKYLPOLYSACCHARIDES HAVING A LOW ACID BREAKDOWN PRODUCT CONTENT SEPPIC SA (FR) 1997-02-12 EP claimed
EP-0633300-A1 Viscosity-stable high solids rosin-phenolic resin solutions WESTVACO CORPORATION (US) 1995-01-11 EP claimed
JP-60013704-A None JP disclosed
EP-4674928-A1 INTUMESCENT FIRE PROTECTION DISPERSIONS DOYMA GmbH & Co (DE) 2026-01-07 EP disclosed
US-20250144266-A1 HEMORRHAGE MANAGEMENT SYSTEM THE TEXAS A&M UNIVERSITY SYSTEM 2025-05-08 US disclosed
US-12220491-B2 Hemorrhage management system LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2025-02-11 US disclosed
US-4639256-A Cold flow improving additive compound and fuel composition containing same MOBIL OIL CORPORATION (US) 1987-01-27 US disclosed
US-4607023-A DIURETICS, POLYPEPTIDES L'INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) 1986-08-19 US disclosed
EP-0140731-A2 Natriuretic factors INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) 1985-05-08 EP disclosed
JP-S6013704-A IMPROVED INSECTICIDE COMPOSITION OTSUKA CHEM CO LTD 1985-01-24 JP disclosed
US-4285789-A COATING A CATHODE WITH A POLYETHERURETHANE COPOLYMER HAVING TERTIARY AMINE, QUARTENARY AMMONIUM, AND BLOCKED ISOCYANATE GROUPS MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1981-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077205-B2 Synthetic compound for improving efficiency of transfection CETP, LNPEP, MTTP TSHR 2865/4885
US-20190083654-A1 Synthetic Compound for Improving Efficiency of Transfection CETP, LNPEP, MTTP TSHR 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.