Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141255 | 0.72 | MEN1 (0.30) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL19932223 | 0.65 | CHEK1 (0.37) | KMT2ADRD1KDRDYRK1A | |
| SCHEMBL382451 | 0.60 | NPC1 (0.35) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL4610872 | 0.60 | NPC1 (0.39) | MEN1KMT2AF2LMNACHRM2 | |
| Water SCHEMBL11162060 | 0.59 | NPC1 (0.34) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL18682060 | 0.53 | CYP3A4 (0.47) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL10070929 | 0.53 | CYP3A4 (0.47) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL10659030 | 0.53 | — | — | |
| SCHEMBL145891 | 0.53 | ALDH1A1 (0.77) | MEN1KMT2AF2LMNACHRM2 | |
| SCHEMBL29367325 | 0.53 | ALDH1A1 (0.77) | MEN1KMT2AF2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861391-A4 | SUBSTITUTED SULFOXIDE COMPOUNDS, METHODS FOR PREPARING THE SAME AND USE THEREOF | LIVZON PHARMACEUTICAL GROUP IN (CN) | 2008-11-05 | — | — | EP | disclosed |
| EP-1861391-A1 | SUBSTITUTED SULFOXIDE COMPOUNDS, METHODS FOR PREPARING THE SAME AND USE THEREOF | Livzon Pharmaceutical Group Inc. (CN) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006099810-A1 | SUBSTITUTED SULFOXIDE COMPOUNDS, METHODS FOR PREPARING THE SAME AND USE THEREOF | LIVZON PHARMACEUTICAL GROUP INC. (CN) | 2006-09-28 | — | — | WO | disclosed |