Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654131 | 0.87 | POLB (0.30) | — | |
| SCHEMBL10017928 | 0.71 | CES2 (0.46) | SMN1; SMN2HSD17B10CES2CES1TSHR | |
| SCHEMBL23764899 | 0.71 | SMN1; SMN2 (0.35) | SMN1; SMN2HSD17B10CES2CES1NOS2 | |
| SCHEMBL13246768 | 0.69 | CES2 (0.50) | SMN1; SMN2HSD17B10CES2CES1TSHR | |
| SCHEMBL12895713 | 0.69 | CES2 (0.50) | SMN1; SMN2HSD17B10CES2CES1TSHR | |
| SCHEMBL23507210 | 0.69 | CES2 (0.43) | SMN1; SMN2HSD17B10CES2CES1TSHR | |
| SCHEMBL2526738 | 0.69 | NOS2 (0.42) | SMN1; SMN2HSD17B10CES2CES1NOS2 | |
| SCHEMBL23764897 | 0.69 | CES2 (0.38) | SMN1; SMN2HSD17B10CES2CES1NOS2 | |
| SCHEMBL22060690 | 0.69 | CES2 (0.50) | SMN1; SMN2HSD17B10CES2CES1TSHR | |
| SCHEMBL408177 | 0.69 | CES2 (0.50) | SMN1; SMN2HSD17B10CES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986598-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | Merck Patent GmbH (DE) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093252-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | MERCK PATENT GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |