Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652325 | 0.90 | LMNA (0.45) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL2965158 | 0.85 | LMNA (0.55) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL4653551 | 0.85 | LMNA (0.51) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL4653975 | 0.84 | LMNA (0.50) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL4653971 | 0.83 | LMNA (0.49) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL22078938 | 0.80 | LMNA (0.45) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL29431903 | 0.80 | HPGD (0.58) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL534051 | 0.80 | HPGD (0.58) | LMNAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL4653723 | 0.80 | LMNA (0.54) | LMNATAS1R3TAS1R1ALDH1A1TSHR | |
| SCHEMBL4653494 | 0.79 | LMNA (0.53) | LMNAALDH1A1TSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | claimed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-0643035-B1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | KAO CORP (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| WO-1996017589-A1 | METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS | KAO CORPORATION (JP) | 1996-06-13 | — | — | WO | disclosed |
| EP-0643035-A1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | Kao Corporation (JP) | 1995-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | LMNA 2112/4885TAS1R3 112/4885TAS1R1 144/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | LMNA 142/4885TAS1R3 2718/4885TAS1R1 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.