Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357179 | 0.91 | SIGMAR1 (0.67) | SIGMAR1KCNH2 | |
| SCHEMBL1356623 | 0.90 | SIGMAR1 (0.63) | SIGMAR1KCNH2 | |
| SCHEMBL4654497 | 0.81 | SIGMAR1 (0.56) | SIGMAR1KCNH2 | |
| SCHEMBL1356697 | 0.79 | SIGMAR1 (0.63) | SIGMAR1KCNH2 | |
| SCHEMBL1356396 | 0.78 | SIGMAR1 (0.67) | SIGMAR1KCNH2 | |
| SCHEMBL1356864 | 0.78 | SIGMAR1 (0.65) | SIGMAR1KCNH2 | |
| SCHEMBL1356847 | 0.78 | SIGMAR1 (0.55) | SIGMAR1KCNH2 | |
| SCHEMBL4655441 | 0.78 | SIGMAR1 (0.67) | SIGMAR1KCNH2 | |
| SCHEMBL1357037 | 0.77 | SIGMAR1 (0.51) | SIGMAR1KCNH2 | |
| SCHEMBL1357575 | 0.75 | KDM4E (0.46) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994008-A2 | IMIDAZOLE COMPOUNDS HAVING PHARMACEUTICAL ACTIVITY TOWARDS THE SIGMA RECEPTOR | Laboratorios del Dr. Esteve S.A. (ES) | 2008-11-26 | — | — | EP | claimed |
| WO-2007098967-A2 | IMIDAZOLE COMPOUNDS HAVING PHARMACEUTICAL ACTIVITY TOWARDS THE SIGMA RECEPTOR | LABORATORIOS DEL DR.ESTEVE, S.A. (ES) | 2007-09-07 | — | — | WO | claimed |