Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251861 | 0.84 | L3MBTL1 (0.38) | CPB2EPHX2KMT2ACA2CA1 | |
| SCHEMBL19177556 | 0.76 | KMT2A (0.43) | KMT2ANOD1FOLH1PRSS1TMPRSS15 | |
| SCHEMBL4300867 | 0.74 | NOD1 (0.44) | KMT2ANOD1FOLH1PRSS1TMPRSS15 | |
| SCHEMBL19177222 | 0.74 | GNPAT (0.44) | KMT2ANOD1FOLH1CA2CA1 | |
| SCHEMBL27857032 | 0.74 | KMT2A (0.47) | KMT2ANOD1FOLH1PRSS1TMPRSS15 | |
| SCHEMBL15017971 | 0.74 | GNPAT (0.44) | KMT2ANOD1FOLH1CA2CA1 | |
| SCHEMBL156957 | 0.74 | GNPAT (0.44) | KMT2ANOD1FOLH1CA2CA1 | |
| SCHEMBL156956 | 0.74 | GNPAT (0.44) | KMT2ANOD1FOLH1CA2CA1 | |
| SCHEMBL15822646 | 0.73 | KMT2A (0.48) | KMT2ANOD1FOLH1PRSS1TMPRSS15 | |
| SCHEMBL15822647 | 0.73 | KMT2A (0.48) | KMT2ANOD1FOLH1PRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888111-A4 | MODULATION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) ACTIVITY | AVANT IMMUNOTHERAPEUTICS INC (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1888111-A1 | MODULATION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) ACTIVITY | Avant Immunotherapeutics, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006133196-A1 | MODULATION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) ACTIVITY | AVANT IMMUNOTHERAPEUTICS, INC. (US) | 2006-12-14 | — | — | WO | disclosed |
| US-20060276400-A1 | Modulation of cholesteryl ester transfer protein (CETP) activity | AVANT IMMUNOTHERAPEUTICS, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7078036-B2 | Modulation of cholesteryl ester transfer protein (CETP) activity | AVANT IMMUNOTHERAPEUTICS, INC. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040087481-A1 | Modulation of cholesteryl ester transfer protein (CETP) activity | CELLDEX THERAPEUTICS, INC. | 2004-05-06 | — | — | US | disclosed |
| US-20030108559-A1 | Modulation of cholesteryl ester transfer protein (CETP) activity | CELLDEX THERAPEUTICS, INC. | 2003-06-12 | — | — | US | disclosed |
| US-6555113-B1 | Elevating the ratio of circulating HDL to circulating LDL by administering a peptide conjugate of a helper T cell epitope portion linked to a B cell epitope portion; decrease in development of atherosclerotic lesions | AVANT IMMUNOTHERAPEUTICS, INC. | 2003-04-29 | — | — | US | disclosed |
| US-6410022-B1 | Modulation of cholesteryl ester transfer protein (CETP) activity | AVANT IMMUNOTHERAPEUTICS, INC. | 2002-06-25 | — | — | US | disclosed |
| US-20020042364-A1 | Modulation of cholesteryl ester transfer protein (CETP) activity | RITTERSHAUS CHARLES W (US) | 2002-04-11 | — | — | US | disclosed |
| EP-1024825-A1 | XENOGENEIC CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) FOR MODULATION OF CETP ACTIVITY | Avant Immunotherapeutics, Inc. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020302-A1 | XENOGENEIC CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) FOR MODULATION OF CETP ACTIVITY | AVANT IMMUNOTHERAPEUTICS, INC. (US) | 1999-04-29 | — | — | WO | disclosed |