Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.47 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.47 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.47 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.47 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.47 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.47 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.47 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654826 | 1.00 | MGAM (0.47) | MGAMGAASIPTPN1MGAM2 | |
| SCHEMBL6654666 | 0.92 | ALOX15 (0.51) | ALOX15TDP1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL6653790 | 0.92 | ALOX15 (0.51) | ALOX15TDP1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL4652347 | 0.85 | TRPV1 (0.53) | MGAMGAASIPTPN1MGAM2 | |
| SCHEMBL4652344 | 0.85 | TRPV1 (0.53) | MGAMGAASIPTPN1MGAM2 | |
| SCHEMBL24183242 | 0.85 | ALOX15 (0.53) | MGAMGAASIPTPN1MGAM2 | |
| SCHEMBL4653412 | 0.82 | ALOX15 (0.53) | ALOX15TDP1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL4653415 | 0.82 | ALOX15 (0.53) | ALOX15TDP1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL4652487 | 0.81 | TRPV1 (0.56) | ALOX15TDP1ALDH1A1MTNR1AKDM4E | |
| SCHEMBL4652491 | 0.81 | TRPV1 (0.56) | ALOX15TDP1ALDH1A1MTNR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | claimed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-0643035-B1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | KAO CORP (JP) | 1999-09-01 | — | — | EP | disclosed |
| US-5646184-A | SEBACEOUS SECRETION INHIBITORY ACTIVITY | KAO CORPORATION (JP) | 1997-07-08 | — | — | US | disclosed |
| WO-1996017589-A1 | METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS | KAO CORPORATION (JP) | 1996-06-13 | — | — | WO | disclosed |
| EP-0643035-A1 | DERMATOLOGIC PREPARATION AND NOVEL BENZOIC ACID DERIVATIVE | Kao Corporation (JP) | 1995-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | MGAM 2516/4885GAA 842/4885SI 2384/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | MGAM 391/4885GAA 35/4885SI 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.