Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463 | 0.98 | PAM (0.66) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Benzene SCHEMBL27612926 | 0.98 | PAM (0.66) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| SCHEMBL278485 | 0.98 | PAM (0.66) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Ethylene SCHEMBL28169506 | 0.96 | PAM (0.63) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Butadiene SCHEMBL5146753 | 0.93 | PAM (0.59) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| SCHEMBL28857182 | 0.93 | PAM (0.59) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Maleic Acid SCHEMBL8841066 | 0.91 | PAM (0.58) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Dimethylamine SCHEMBL29567163 | 0.91 | PAM (0.58) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Methacrylic Acid SCHEMBL5875035 | 0.91 | PAM (0.58) | PAMMAOBHAO1HDAC1ALDH1A1 | |
| Acrylic Acid SCHEMBL448097 | 0.91 | PAM (0.58) | PAMMAOBHAO1HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836936-B1 | covering structure | DAINIPPON PRINTING CO LTD (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1658971-B1 | Laminated structure | DAINIPPON PRINTING CO LTD (JP) | 2007-12-26 | — | — | EP | disclosed |
| EP-1658971-A1 | Laminated structure | Dai Nippon Printing Co., Ltd. (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-6218017-B1 | A LAMINATED STRUCTURE CONTAINING A HEAT SEALANT LAYER, AN ANTISTATIC LAYER OF A BISAMMONIUM ORGANIC SULFUR SEMICONDUCTOR FORMED ON ONE SURFACE OF HEAT SEALANT LAYER, AN ORIENTED RESIN LAYER | DAI NIPPON PRINTING CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |