SCHEMBL4654883

SCHEMBL4654883

c1ccc2nc3c(ccc4nc5ccccc5nc43)nc2c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.69
ALDH1A1 P00352 4/20 0.61
GAA P10253 3/20 0.61
RAB9A P51151 2/20 0.61
KMT2A Q03164 2/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NQO2 P16083 8/20 0.54
NPC1 O15118 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 2/20 0.52
THRB P10828 1/20 0.52
MAPK1 P28482 1/20 0.52
BLM P54132 1/20 0.52
ATM Q13315 1/20 0.52
ACHE P22303 2/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
CACNA1B Q00975 1/20 0.48
APBA1 Q02410 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31391239 0.86 MYC (0.63) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL16094567 0.83 MAPT (0.48) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL8206153 0.83 MAPT (0.48) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29402115 0.83 MAPT (0.71) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL2246928 0.83 MAPT (0.71) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL29581806 0.83 MAPT (0.71) MAPTALDH1A1GAARAB9AKMT2A
Phenazine SCHEMBL29356959 0.83 MAPT (1.00) MAPTALDH1A1GAARAB9AKMT2A
Phenazine SCHEMBL27643128 0.83 MAPT (1.00) MAPTALDH1A1GAARAB9AKMT2A
Phenazine SCHEMBL9049 0.83 MAPT (1.00) MAPTALDH1A1GAARAB9AKMT2A
SCHEMBL27969901 0.80 MAPT (0.60) MAPTALDH1A1GAARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260203-B Quinoxaline phenazine luminescent material and application thereof 浙江工业大学 2024-06-14 CN claimed
CN-115260203-A Quinoxalino-phenazine luminescent material and application thereof 浙江工业大学 2022-11-01 CN claimed
US-6560004-B2 Coupled electrochromic compounds with photostable dication oxidation states GENTEX CORPORATION 2003-05-06 US claimed
US-20020018281-A1 Coupled electrochromic compounds with photostable dication oxidation states THEISTE DAVID A (US) 2002-02-14 US claimed
US-6249369-B1 Coupled electrochromic compounds with photostable dication oxidation states GENTEX CORPORATION 2001-06-19 US claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US claimed
US-12252498-B2 Electrochromic devices having a buffer system GENTEX CORPORATION (US) 2025-03-18 US disclosed
EP-4511696-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2025-02-26 EP disclosed
CN-119032318-A Electrochromic device with buffer system 金泰克斯公司 2024-11-26 CN disclosed
CN-115260203-B Quinoxaline phenazine luminescent material and application thereof 浙江工业大学 2024-06-14 CN disclosed
US-20230382938-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2023-11-30 US disclosed
WO-2023205262-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM GENTEX CORPORATION (US) 2023-10-26 WO disclosed
CN-115348996-A Adhesive composition 日本曹达株式会社 2022-11-15 CN disclosed
US-6249369-B1 Coupled electrochromic compounds with photostable dication oxidation states GENTEX CORPORATION 2001-06-19 US disclosed
WO-2001040858-A1 ELECTROACTIVE MATERIALS AND BENEFICIAL AGENTS HAVING A SOLUBLIZING MOIETY GENTEX CORPORATION (US) 2001-06-07 WO disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382938-A1 ELECTROCHROMIC DEVICES HAVING A BUFFER SYSTEM HCN2, HCN1, HCN3 MAPT 3087/4885ALDH1A1 1718/4885GAA 1756/4885
US-12252498-B2 Electrochromic devices having a buffer system HCN2, HCN1, HCN3 MAPT 3087/4885ALDH1A1 1718/4885GAA 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.