Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654077 | 0.89 | GAA (0.76) | GAAALDH1A1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL941445 | 0.85 | GAA (0.56) | GAAALDH1A1LMNAMAPTPKM | |
| SCHEMBL7349545 | 0.81 | ALDH1A1 (0.52) | GAAALDH1A1LMNAMAPTPKM | |
| SCHEMBL3283784 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1LMNAMAPTPKM | |
| SCHEMBL30444601 | 0.79 | KMT2A (0.62) | ALDH1A1NPC1RAB9AMAPTNSD2 | |
| SCHEMBL4653945 | 0.78 | GAA (0.45) | GAAALDH1A1LMNAMAPTPKM | |
| SCHEMBL20074155 | 0.78 | ALDH1A1 (0.49) | GAAALDH1A1LMNANPC1RAB9A | |
| SCHEMBL14072996 | 0.78 | TSHR (0.61) | ALDH1A1LMNARAB9AMAPTPRMT5 | |
| SCHEMBL7348989 | 0.77 | MAPT (0.63) | GAAALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL10538281 | 0.77 | ALDH1A1 (0.59) | GAAALDH1A1MAPTPKMNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844029-B1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | SERVIER LAB (FR) | 2008-11-12 | — | — | EP | disclosed |
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | LES LABORATOIRES SERVIER (FR) | 2008-05-15 | — | — | US | disclosed |
| EP-1844029-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | Les Laboratoires Servier (FR) | 2007-10-17 | — | — | EP | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| WO-2006079720-A1 | NOVEL HETEROCYCLIC OXIME DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS HYPOGLYCAEMIC OR HYPOLIPIDEMIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113974-A1 | Heterocyclic Oxime Compounds, A Process For Their Preparation And Pharmaceutical Compositions Containing Them. | CBR1, CYP3A7, CYP2C9 | GAA 2685/4885ALDH1A1 521/4885AKR1C3 115/4885 |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | GAA 1112/4885ALDH1A1 207/4885AKR1C3 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.