SCHEMBL4654977

SCHEMBL4654977

CCCCCCCCCC(Oc1cccc(F)c1F)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.47
PPARA Q07869 4/20 0.47
CTRC Q99895 1/20 0.45
PTGES O14684 1/20 0.42
ALOX5 P09917 1/20 0.42
PTPN1 P18031 1/20 0.40
MAPT P10636 1/20 0.40
ALDH2 P05091 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
FAAH O00519 6/20 0.38
ALDH1A1 P00352 1/20 0.38
FOLH1 Q04609 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654231 0.89 PPARG (0.59) PPARGPPARACTRCPTGESALOX5
SCHEMBL3948949 0.89 PPARG (0.51) PPARGPPARAPTGESALOX5MAPT
SCHEMBL30639267 0.84 CTRC (0.54) PPARGPPARACTRCPTGESALOX5
SCHEMBL568643 0.80 CTRC (0.50) PPARGPPARACTRCPTGESALOX5
SCHEMBL11521450 0.80 KMT2A (0.53) PPARGPPARACTRCPTGESALOX5
SCHEMBL14565994 0.80 CTRC (0.50) PPARGPPARACTRCPTGESALOX5
SCHEMBL568454 0.80 CTRC (0.50) PPARGPPARACTRCPTGESALOX5
SCHEMBL8065096 0.79 KDM4E (0.49) PPARGPPARACTRCPTGESALOX5
SCHEMBL9322236 0.78 CTRC (0.49) PPARGPPARACTRCPTGESALOX5
SCHEMBL547407 0.78 KDM4E (0.56) PPARGPPARACTRCPTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP disclosed
EP-1188782-B1 Polyhydroxyalkanoate and manufacturing method thereof CANON KK (JP) 2007-04-04 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-7078200-B2 Method for manufacturing a polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2006-07-18 US disclosed
US-7056708-B2 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
EP-1367078-B1 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KK (JP) 2006-04-19 EP disclosed
EP-1130043-B1 Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KK (JP) 2006-01-25 EP disclosed
US-6861550-B2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US disclosed
US-20040092702-A1 Method for manufacturing a polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2004-05-13 US disclosed
US-6479621-B2 PRODUCED BY MICROORGANISMS; BIODEGRADATION, BIOCOMPATIBILITY CANON KABUSHIKI KAISHA (JP) 2002-11-12 US disclosed
US-20020160467-A1 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-10-31 US disclosed
US-20020065389-A1 Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1188782-A2 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-03-20 EP disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US disclosed
EP-1130042-A2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP disclosed
EP-1130043-A2 Polyhydroxylalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed