SCHEMBL3948949

SCHEMBL3948949

CCCC(Oc1cccc(F)c1F)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 14/20 0.51
PPARA Q07869 11/20 0.51
EGLN1 Q9GZT9 1/20 0.38
MAPT P10636 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654977 0.89 PPARG (0.47) PPARGPPARAMAPTPTGESALOX5
SCHEMBL7507747 0.88 PPARG (0.66) PPARGPPARAMAPTPTGESALOX5
SCHEMBL6378220 0.87 PPARG (0.49) PPARGPPARAPTGESALOX5
SCHEMBL15676622 0.78 PPARG (0.42) PPARGPPARAEGLN1MAPTPTGS1
SCHEMBL11360035 0.78 PPARG (0.51) PPARGPPARAMAPTPTGESALOX5
SCHEMBL4654231 0.77 PPARG (0.59) PPARGPPARAMAPTPTGESALOX5
SCHEMBL8082709 0.76 PPARG (0.56) PPARGPPARAPTGESALOX5
SCHEMBL2571460 0.76 PPARG (0.56) PPARGPPARAMAPTPTGS1PTGS2
SCHEMBL10877367 0.76 PPARA (0.56) PPARGPPARAMAPT
SCHEMBL6234211 0.75 PPARG (0.69) PPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1275378-B1 Particulate construct comprising polyhydroxyalkanoate and method for producing it CANON KK (JP) 2009-04-15 EP disclosed