SCHEMBL4655074

SCHEMBL4655074

O=C(O)CC(O)CCc1ccc(C(F)(F)F)cc1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 11/20 0.62
MMP13 P45452 10/20 0.62
MMP2 P08253 1/20 0.62
MMP9 P14780 1/20 0.62
MMP14 P50281 1/20 0.62
PTGFR P43088 1/20 0.52
FFAR1 O14842 1/20 0.48
FDFT1 P37268 2/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258389 0.81 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL18063390 0.81 PTGFR (0.49) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1139516 0.81 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL8333817 0.79 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4745347 0.79 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL687094 0.79 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL6460810 0.78 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL5613511 0.78 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1139059 0.78 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL3205639 0.78 MMP12 (0.69) MMP12MMP13MMP2MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
CN-101528691-B Matrix metalloproteinase inhibitors RANBAXY LAB LTD 2014-11-26 CN disclosed
CN-101528691-A Matrix metalloproteinase inhibitors RANBAXY LAB LTD (IN) 2009-09-09 CN disclosed
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed