Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.73 |
| ▸ | APAF1 | O14727 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4655149 | 1.00 | DNM1 (0.73) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL4047250 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL4047246 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL157761 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL157763 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL3802505 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| SCHEMBL6549116 | 0.98 | DNM1 (0.71) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Hydrochloric Acid SCHEMBL1029164 | 0.95 | DNM1 (0.73) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Water SCHEMBL5704109 | 0.95 | APAF1 (0.70) | DNM1APAF1HSP90AA1RAD52MEN1 | |
| Water SCHEMBL8017017 | 0.95 | APAF1 (0.70) | DNM1APAF1HSP90AA1RAD52MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111718716-A | Nanostructures with inorganic ligands for electroluminescent devices | 纳米系统公司 | 2020-09-29 | — | — | CN | claimed |
| US-11268022-B2 | Nanostructures with inorganic ligands for electroluminescent devices | NANOSYS, INC. (US) | 2022-03-08 | — | — | US | disclosed |
| CN-113260916-A | Optical activation of chemical entities in electrophoretic dispersions for display devices | 哈里恩显示器公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-111718716-A | Nanostructures with inorganic ligands for electroluminescent devices | 纳米系统公司 | 2020-09-29 | — | — | CN | disclosed |
| US-20200299575-A1 | NANOSTRUCTURES WITH INORGANIC LIGANDS FOR ELECTROLUMINESCENT DEVICES | NANOSYS, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| EP-1228717-B1 | Antimicrobial and deodorant cosmetic brush and method of producing the same | NAKAMURA KENJI (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6604531-B2 | Natural bristles (animal hairs) are submerged in a solution containing at least one or more kinds of cationic surfactants selected from alkyl ammonium salts containing a quaternary nitrogen or alkylbenzyl ammonium salts containing a quaternary | NAKAMURA KENJI (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020144703-A1 | Antimicrobial and deodorant cosmetic brush and method of producing the same | NAKAMURA KENJI (JP) | 2002-10-10 | — | — | US | disclosed |
| EP-1228717-A2 | Antimicrobial and deodorant cosmetic brush and method of producing the same | Kenji, Nakamura, Taiki Awaji Factory Co., Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-0891136-B1 | HERBICIDAL AND PLANT GROWTH REGULANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORP (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0891136-A1 | HERBICIDAL AND PLANT GROWTH REGULANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5858921-A | Glyphosate herbicidal and plant growth regulant compositions and their use | ALBEMARLE CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| US-5710103-A | HERBICIDES | ALBEMARLE CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1997036489-A1 | HERBICIDAL AND PLANT GROWTH REGULANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 1997-10-09 | — | — | WO | disclosed |