Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297316 | 0.98 | EPHX1 (0.46) | EPHX1SHBGCYP1A2METAP1SIGMAR1 | |
| SCHEMBL5824287 | 0.91 | EPHX1 (0.44) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL28026127 | 0.91 | EPHX1 (0.39) | EPHX1SHBGCYP1A2SIGMAR1DNM1 | |
| SCHEMBL4655240 | 0.90 | DNM1 (0.38) | SHBGCYP1A2METAP1DNM1ALDH1A1 | |
| SCHEMBL11440474 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL2593250 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL11440912 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL16319347 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL10929841 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR | |
| SCHEMBL16110550 | 0.89 | EPHX1 (0.43) | EPHX1SHBGCYP1A2SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986598-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | Merck Patent GmbH (DE) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093252-A1 | UV FILTER CAPSULES COMPRISING AN AMINOSUBSTITUTED HYDROXYBENZOPHENONE | MERCK PATENT GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |