Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656252 | 0.86 | ECE1 (0.54) | ECE1F10PTGDR2CCR2 | |
| SCHEMBL3153127 | 0.84 | RAB9A (0.60) | ECE1F10PTGDR2MAPT | |
| SCHEMBL3579347 | 0.82 | ECE1 (0.51) | ECE1F10PTGDR2CCR2 | |
| SCHEMBL4655342 | 0.81 | ECE1 (0.49) | ECE1F10PTGDR2CCR2 | |
| SCHEMBL3156857 | 0.81 | ECE1 (0.50) | ECE1F10PTGDR2MAPTALDH1A1 | |
| SCHEMBL3150066 | 0.80 | NPC1 (0.52) | ECE1F10PTGDR2MAPTTP53 | |
| SCHEMBL4145769 | 0.80 | ECE1 (0.51) | ECE1F10PTGDR2ALDH1A1CCR2 | |
| SCHEMBL975576 | 0.79 | ECE1 (0.47) | ECE1F10PTGDR2CCR2 | |
| SCHEMBL973614 | 0.79 | ECE1 (0.47) | ECE1F10PTGDR2MAPK1CCR2 | |
| SCHEMBL3158981 | 0.79 | ECE1 (0.47) | ECE1F10PTGDR2TP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |