Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 10/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579347 | 0.86 | ECE1 (0.51) | ECE1F10PTGDR2MAOBCCR2 | |
| SCHEMBL3153127 | 0.86 | RAB9A (0.60) | ECE1F10PTGDR2LMNA | |
| SCHEMBL4655307 | 0.86 | ECE1 (0.49) | ECE1F10PTGDR2CCR2 | |
| SCHEMBL3156857 | 0.85 | ECE1 (0.50) | ECE1F10PTGDR2MAOB | |
| SCHEMBL4655342 | 0.84 | ECE1 (0.49) | ECE1F10PTGDR2MAOBCCR2 | |
| SCHEMBL4655266 | 0.82 | ECE1 (0.56) | ECE1F10PTGDR2MAOBTHRB | |
| SCHEMBL4656308 | 0.82 | ECE1 (0.49) | ECE1F10MAOBCCR2 | |
| SCHEMBL4656230 | 0.82 | ECE1 (0.60) | ECE1F10PTGDR2MAOBCCR2 | |
| SCHEMBL3150066 | 0.82 | NPC1 (0.52) | ECE1F10PTGDR2MAOBL3MBTL1 | |
| SCHEMBL3580566 | 0.82 | NPC1 (0.52) | ECE1F10MAOBCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | claimed |
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |