Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656155 | 0.94 | PPARG (0.56) | PPARGECE1 | |
| SCHEMBL3574151 | 0.92 | PPARG (0.64) | PPARGECE1 | |
| SCHEMBL4655349 | 0.91 | PPARG (0.54) | PPARGECE1 | |
| SCHEMBL4655243 | 0.91 | PPARG (0.56) | PPARGECE1 | |
| SCHEMBL4656134 | 0.89 | ECE1 (0.52) | PPARGECE1 | |
| SCHEMBL3578189 | 0.89 | PPARG (0.55) | PPARGABCB1ECE1 | |
| SCHEMBL4655390 | 0.89 | MAOB (0.50) | PPARGABCB1ECE1RXFP1 | |
| SCHEMBL4656151 | 0.88 | PPARG (0.49) | PPARGECE1 | |
| SCHEMBL4655303 | 0.86 | ECE1 (0.49) | PPARGABCB1ECE1RXFP1 | |
| SCHEMBL4656135 | 0.86 | PPARG (0.53) | PPARGCCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | claimed |
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |