Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578189 | 0.95 | PPARG (0.55) | PPARGMAPTPLGPLAUPLAT | |
| SCHEMBL4655397 | 0.89 | MAOB (0.48) | PPARGMAPTCCR9F10 | |
| SCHEMBL3574151 | 0.88 | PPARG (0.64) | PPARG | |
| SCHEMBL4656155 | 0.88 | PPARG (0.56) | PPARG | |
| SCHEMBL4655400 | 0.86 | PPARG (0.49) | PPARGMAPTF10 | |
| SCHEMBL4655243 | 0.86 | PPARG (0.56) | PPARG | |
| SCHEMBL4655334 | 0.86 | PPARG (0.61) | PPARGCCR9 | |
| SCHEMBL4655349 | 0.86 | PPARG (0.54) | PPARGF10 | |
| SCHEMBL4655329 | 0.84 | ECE1 (0.49) | PPARGMAPTF10 | |
| SCHEMBL4656151 | 0.82 | PPARG (0.49) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |