SCHEMBL4656155

SCHEMBL4656155

Cn1ccc2cc(NC(=O)c3cc4cc(C(F)(F)F)ccc4n3Cc3cccc(C(F)(F)F)c3)ccc21

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.56
ECE1 P42892 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3574151 0.94 PPARG (0.64) PPARGECE1
SCHEMBL4655334 0.94 PPARG (0.61) PPARGECE1
SCHEMBL4655243 0.94 PPARG (0.56) PPARGECE1
SCHEMBL4656151 0.94 PPARG (0.49) PPARGECE1
SCHEMBL4655349 0.94 PPARG (0.54) PPARGECE1
SCHEMBL4656134 0.94 ECE1 (0.52) PPARGECE1
SCHEMBL3578189 0.92 PPARG (0.55) PPARGECE1
SCHEMBL4656135 0.88 PPARG (0.53) PPARG
SCHEMBL4655262 0.87 ECE1 (0.51) PPARGECE1
SCHEMBL4655387 0.86 ECE1 (0.51) PPARGECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101010297-B N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use SANOFI AVENTIS 2011-07-27 CN claimed
EP-1776340-B1 N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE SANOFI AVENTIS (FR) 2008-12-03 EP claimed