Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655397 | 0.90 | MAOB (0.48) | ABCB1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL4655329 | 0.90 | ECE1 (0.49) | ABCB1MAPTKDM4ELMNAMAOB | |
| SCHEMBL3579347 | 0.89 | ECE1 (0.51) | ABCB1MAOBECE1F10NOTUM | |
| SCHEMBL4655292 | 0.89 | MAOB (0.50) | MAPTKMT2AKDM4EMEN1CYP1A2 | |
| SCHEMBL4656270 | 0.89 | F10 (0.46) | ABCB1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL4655386 | 0.87 | ECE1 (0.51) | MAOBECE1F10NOTUMPPARG | |
| SCHEMBL4655390 | 0.87 | MAOB (0.50) | ABCB1KDM4ENPSR1MAOBECE1 | |
| SCHEMBL4655266 | 0.87 | ECE1 (0.56) | MAPTKDM4ELMNANPSR1MAOB | |
| SCHEMBL4655318 | 0.87 | ECE1 (0.51) | MAPTKDM4ENPSR1MAOBECE1 | |
| SCHEMBL4656158 | 0.87 | MAOB (0.46) | ABCB1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | claimed |
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |