Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655329 | 0.95 | ECE1 (0.49) | MAOBPPARGEPHX2CCR2ECE1 | |
| SCHEMBL4655292 | 0.91 | MAOB (0.50) | MAOBPPARGEPHX2CCR2ECE1 | |
| SCHEMBL4655350 | 0.90 | CCR2 (0.51) | MAOBPPARGCCR2ECE1PTGER3 | |
| SCHEMBL4655353 | 0.90 | ABCB1 (0.48) | MAOBPPARGEPHX2ECE1F10 | |
| SCHEMBL4656135 | 0.89 | PPARG (0.53) | PPARGF10CCR9MAPT | |
| SCHEMBL4655318 | 0.89 | ECE1 (0.51) | MAOBPPARGEPHX2ECE1CNR1 | |
| SCHEMBL4656158 | 0.88 | MAOB (0.46) | MAOBPPARGEPHX2ECE1PTGER3 | |
| SCHEMBL4655386 | 0.87 | ECE1 (0.51) | MAOBPPARGCCR2ECE1F10 | |
| SCHEMBL3579347 | 0.87 | ECE1 (0.51) | MAOBCCR2ECE1F10ABCB1 | |
| SCHEMBL4656153 | 0.86 | ECE1 (0.50) | MAOBPPARGEPHX2ECE1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |