SCHEMBL465541

SCHEMBL465541

NC(=O)Nc1ccccc1Cc1ccccc1NC(N)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
KDM4E B2RXH2 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 5/20 0.48
RECQL P46063 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
MAPT P10636 3/20 0.46
HPGD P15428 1/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29840042 1.00 GAA (0.52) GAAKDM4EL3MBTL1ALDH1A1RECQL
SCHEMBL2419022 0.88 L3MBTL1 (0.68) GAAKDM4EL3MBTL1ALDH1A1RECQL
SCHEMBL1953684 0.85 MAPT (0.62) GAAL3MBTL1ALDH1A1SMN1; SMN2GRIN2D
SCHEMBL29581227 0.85 MAPT (0.62) GAAL3MBTL1ALDH1A1SMN1; SMN2GRIN2D
SCHEMBL7837046 0.85 ALDH1A1 (0.61) GAAKDM4EL3MBTL1ALDH1A1RECQL
SCHEMBL27483868 0.85 GAA (0.50) GAAKDM4EL3MBTL1ALDH1A1RECQL
SCHEMBL28832931 0.84 L3MBTL1 (0.54) GAAKDM4EL3MBTL1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL28825350 0.83 MAPT (0.61) GAAL3MBTL1ALDH1A1SMN1; SMN2GRIN2D
SCHEMBL28644237 0.83 GAA (0.48) GAAKDM4EL3MBTL1ALDH1A1RECQL
SCHEMBL10562641 0.83 GAA (0.48) GAAKDM4EL3MBTL1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120028032-A1 STRUCTURAL COMPOSITE LAMINATES ZEPHYROS, INC. (US) 2012-02-02 US disclosed
US-8105460-B2 applying the handling layer to the adhesive material to form an adhesive part, handling layer including a solid epoxy resin,( bisphenol a-epichlorohydrin ether type or bisphenol a epoxy), an epxoy/acrylonitrile-butadiene copolymer adduct; activating and curing/crosslinking adhesive mateial ZEPHYROS, INC. (US) 2012-01-31 US disclosed
EP-2160435-B1 TOUGHENED ADHESIVE MATERIAL ZEPHYROS INC (US) 2012-01-11 EP disclosed
WO-2011141148-A2 IMPROVEMENTS IN OR RELATING TO STRUCTURAL ADHESIVES ZEPHYROS INC (US) 2011-11-17 WO disclosed
EP-1790554-B1 Expandable material and fastenable member for sealing, baffling or reinforcing and method of forming same ZEPHYROS INC (US) 2011-09-21 EP disclosed
US-20110220267-A1 PROVISION OF INSERTS ZEPHYROS, INC. (US) 2011-09-15 US disclosed
WO-2011109699-A1 STRUCTURAL COMPOSITE LAMINATE ZEPHYROS, INC. (US) 2011-09-09 WO disclosed
US-20110215632-A1 MANUFACTURE OF SEATS ZEPHYROS INC. 2011-09-08 US disclosed
EP-2350218-A1 PROVISION OF INSERTS Zephyros Inc. (US) 2011-08-03 EP disclosed
EP-2231348-B1 METHOD FOR PRODUCING A JOINT ZEPHYROS INC (US) 2011-05-25 EP disclosed
US-20110098382-A1 STRUCTURAL ADHESIVES ZEPHYROS INC (US) 2011-04-28 US disclosed
EP-2300550-A1 IMPROVEMENTS IN OR RELATING TO THE MANUFACTURE OF SEATS Zephyros Inc. (US) 2011-03-30 EP disclosed
WO-2011032677-A1 IMPROVEMENTS IN OR RELATING TO CAVITY FILLING ZEPHYROS INC (US) 2011-03-24 WO disclosed
US-7892396-B2 Toughened activatable material for sealing, baffling or reinforcing and method of forming same ZEPHYROS, INC. (US) 2011-02-22 US disclosed
WO-2011012997-A2 IMPROVEMENTS IN OR RELATING TO FOAMED INSERTS ZEPHYROS INC 2011-02-03 WO disclosed
EP-2268752-A1 IMPROVEMENTS IN OR RELATING TO STRUCTURAL ADHESIVES Zephyros Inc. (US) 2011-01-05 EP disclosed